Patient derived xenografts (PDX) are models developed for cancer, through the implantation of tissue or cells from a patient tumor into an immunodeficient or humanized mouse. PDX models better represent native tumor diversity and microenvironment, and thus respond to potential cancer drugs in a manner more representative of a human.
We have more than 200 unique PDX models, covering 14 indications, which are fully integrated with our in vitro experimental platform. Our PDX models have been characterized by histology, conservation of phenotype and genotype, gene expression stability, gene mutation status, and response to standard of care (SOC).
If the appropriate model is not available, our experienced team can develop a customized model to match your research needs.
