Title:
Recent trends in drug discovery of covalent binders: the role of boron and benzoxaboroles as reversible covalent binders to target the serine and threonine proteome.
Autor :
Christophe Parsy, PhD, MBA, head of medicinal chemistry at Oncodesign Services.
Abstract :
Molecules based on boron and benzoxaboroles are exciting as reversible covalent binders to target the serine and threonine proteome.
In this blog, Christophe Parsy, Ph.D, MBA provides an overview of their potential as an alternative to irreversible cysteine covalent binders to overcome possible off-target limitations and highlighting the exciting possibilities for future drug discovery.