(1) Bronchiolitis model in mice, induced by Human Respiratory Syncytial Virus (RSV)
Borchers AT, Chang C, Gershwin ME, Gershwin LJ. Respiratory syncytial virus–a comprehensive review. Clin Rev Allergy Immunol. 2013 Dec;45(3):331-79. doi: 10.1007/s12016-013-8368-9. PMID: 23575961; PMCID: PMC7090643.
https://pubmed.ncbi.nlm.nih.gov/23575961/
https://link.springer.com/article/10.1007/s12016-013-8368-9
Taylor G. Animal models of respiratory syncytial virus infection. Vaccine. 2017 Jan 11;35(3):469-480. doi: 10.1016/j.vaccine.2016.11.054. Epub 2016 Nov 29. PMID: 27908639; PMCID: PMC5244256.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5244256/
Ceneviva ZJ, Norlander AE, Stokes Peebles R Jr. Mouse Models of Respiratory Syncytial Virus Infection. Methods Mol Biol. 2022;2506:19-41. doi: 10.1007/978-1-0716-2364-0_2. PMID: 35771461.
https://pubmed.ncbi.nlm.nih.gov/35771461/
Tregoning JS, Yamaguchi Y, Harker J, Wang B, Openshaw PJ. The role of T cells in the enhancement of respiratory syncytial virus infection severity during adult reinfection of neonatally sensitized mice. J Virol. 2008 Apr;82(8):4115-24. doi: 10.1128/JVI.02313-07. Epub 2008 Feb 13. PMID: 18272579; PMCID: PMC2293007.
https://pubmed.ncbi.nlm.nih.gov/18272579/
Sebina I, Phipps S. The Contribution of Neutrophils to the Pathogenesis of RSV Bronchiolitis. Viruses. 2020 Jul 27;12(8):808. doi: 10.3390/v12080808. PMID: 32726921; PMCID: PMC7472258.
https://pubmed.ncbi.nlm.nih.gov/32726921/
(2) Allergic asthma model in mice, induced by House Dust Mice (HDM)
Gao X, Leung TF, Wong GW, Ko WH, Cai M, He EJ, Chu IM, Tsang MS, Chan BC, Ling J, Fan X, Lu L, Lam CW, Wong CK. Meteorin-β/Meteorin like/IL-41 attenuates airway inflammation in house dust mite-induced allergic asthma. Cell Mol Immunol. 2022 Feb;19(2):245-259. doi: 10.1038/s41423-021-00803-8. Epub 2021 Nov 30. PMID: 34848868; PMCID: PMC8803866.
https://pubmed.ncbi.nlm.nih.gov/34848868/
Debeuf N, Haspeslagh E, van Helden M, Hammad H, Lambrecht BN. Mouse Models of Asthma. Curr Protoc Mouse Biol. 2016 Jun 1;6(2):169-184. doi: 10.1002/cpmo.4. PMID: 27248433.
https://pubmed.ncbi.nlm.nih.gov/27248433/
Oikonomou N, Schuijs MJ, Chatzigiagkos A, Androulidaki A, Aidinis V, Hammad H, Lambrecht BN, Pasparakis M. Airway epithelial cell necroptosis contributes to asthma exacerbation in a mouse model of house dust mite-induced allergic inflammation. Mucosal Immunol. 2021 Sep;14(5):1160-1171. doi: 10.1038/s41385-021-00415-5. Epub 2021 May 27. PMID: 34045680; PMCID: PMC8379077.
https://pubmed.ncbi.nlm.nih.gov/34045680/
Ma M, Li G, Qi M, Jiang W, Zhou R. Inhibition of the Inflammasome Activity of NLRP3 Attenuates HDM-Induced Allergic Asthma. Front Immunol. 2021 Aug 3;12:718779. doi: 10.3389/fimmu.2021.718779. PMID: 34413860; PMCID: PMC8369415.
https://pubmed.ncbi.nlm.nih.gov/34413860/
Maes B, Smole U, Vanderkerken M, Deswarte K, Van Moorleghem J, Vergote K, Vanheerswynghels M, De Wolf C, De Prijck S, Debeuf N, Pavie B, Toussaint W, Janssens S, Savvides S, Lambrecht BN, Hammad H. The STE20 kinase TAOK3 controls the development of house dust mite-induced asthma in mice. J Allergy Clin Immunol. 2022 Apr;149(4):1413-1427.e2. doi: 10.1016/j.jaci.2021.08.020. Epub 2021 Sep 8. PMID: 34506849.
https://pubmed.ncbi.nlm.nih.gov/34506849/
(3) Corticoid-resistant asthma in mice, induced by Ovalbumin (OVA) + Influenzae
Essilfie AT, Simpson JL, Dunkley ML, Morgan LC, Oliver BG, Gibson PG, Foster PS, Hansbro PM. Combined Haemophilus influenzae respiratory infection and allergic airways disease drives chronic infection and features of neutrophilic asthma. Thorax. 2012 Jul;67(7):588-99. doi: 10.1136/thoraxjnl-2011-200160. Epub 2012 Mar 3. PMID: 22387445.
https://pubmed.ncbi.nlm.nih.gov/22387445/
Kim RY, Pinkerton JW, Essilfie AT, Robertson AAB, Baines KJ, Brown AC, Mayall JR, Ali MK, Starkey MR, Hansbro NG, Hirota JA, Wood LG, Simpson JL, Knight DA, Wark PA, Gibson PG, O’Neill LAJ, Cooper MA, Horvat JC, Hansbro PM. Role for NLRP3 Inflammasome-mediated, IL-1β-Dependent Responses in Severe, Steroid-Resistant Asthma. Am J Respir Crit Care Med. 2017 Aug 1;196(3):283-297. doi: 10.1164/rccm.201609-1830OC. PMID: 28252317.
https://pubmed.ncbi.nlm.nih.gov/28252317/
(4) Asthma exacerbation model in mice, induced by RSV + HDM combination
Zhang D, Yang J, Zhao Y, Shan J, Wang L, Yang G, He S, Li E. RSV Infection in Neonatal Mice Induces Pulmonary Eosinophilia Responsible for Asthmatic Reaction. Front Immunol. 2022 Feb 2;13:817113. doi: 10.3389/fimmu.2022.817113. PMID: 35185908; PMCID: PMC8847141.
https://pubmed.ncbi.nlm.nih.gov/35185908/
https://www.frontiersin.org/articles/10.3389/fimmu.2022.817113/full
Makino A, Shibata T, Nagayasu M, Hosoya I, Nishimura T, Nakano C, Nagata K, Ito T, Takahashi Y, Nakamura S. RSV infection-elicited high MMP-12-producing macrophages exacerbate allergic airway inflammation with neutrophil infiltration. iScience. 2021 Oct 2;24(10):103201. doi: 10.1016/j.isci.2021.103201. PMID: 34703996; PMCID: PMC8524145.
https://pubmed.ncbi.nlm.nih.gov/34703996/
Matsuse H, Hirose H, Tsuchida T, Fukahori S, Fukushima C, Mizuta Y, Kohno S. Effects of respiratory syncytial virus infection on dendritic cells and cysteinyl leukotrienes in lung tissues of a murine model of asthma. Allergol Int. 2007 Jun;56(2):165-9. doi: 10.2332/allergolint.O-06-476. Epub 2007 May 1. PMID: 17460444.
https://pubmed.ncbi.nlm.nih.gov/17460444/
(5) Lung fibrosis model in mice, induced by Bleomycin delivered IT or by osmotic pumps
Herrmann FE, Hesslinger C, Wollin L, Nickolaus P. BI 1015550 is a PDE4B Inhibitor and a Clinical Drug Candidate for the Oral Treatment of Idiopathic Pulmonary Fibrosis. Front Pharmacol. 2022 Apr 20;13:838449. doi: 10.3389/fphar.2022.838449. PMID: 35517783; PMCID: PMC9065678.
https://www.frontiersin.org/articles/10.3389/fphar.2022.838449/full
Lee R, Reese C, Bonner M, Tourkina E, Hajdu Z, Riemer EC, Silver RM, Visconti RP, Hoffman S. Bleomycin delivery by osmotic minipump: similarity to human scleroderma interstitial lung disease. Am J Physiol Lung Cell Mol Physiol. 2014 Apr 15;306(8):L736-48. doi: 10.1152/ajplung.00210.2013. Epub 2014 Feb 28. PMID: 24583879; PMCID: PMC3989726.
https://pubmed.ncbi.nlm.nih.gov/24583879/
Liang M, Lv J, Zou L, Yang W, Xiong Y, Chen X, Guan M, He R, Zou H. A modified murine model of systemic sclerosis: bleomycin given by pump infusion induced skin and pulmonary inflammation and fibrosis. Lab Invest. 2015 Mar;95(3):342-50. doi: 10.1038/labinvest.2014.145. Epub 2014 Dec 15. PMID: 25502178.
https://www.nature.com/articles/labinvest2014145
Hübner RH, Gitter W, El Mokhtari NE, Mathiak M, Both M, Bolte H, Freitag-Wolf S, Bewig B. Standardized quantification of pulmonary fibrosis in histological samples. Biotechniques. 2008 Apr;44(4):507-11, 514-7. doi: 10.2144/000112729. PMID: 18476815.
https://pubmed.ncbi.nlm.nih.gov/18476815/
Egger C, Gérard C, Vidotto N, Accart N, Cannet C, Dunbar A, Tigani B, Piaia A, Jarai G, Jarman E, Schmid HA, Beckmann N. Lung volume quantified by MRI reflects extracellular-matrix deposition and altered pulmonary function in bleomycin models of fibrosis: effects of SOM230. Am J Physiol Lung Cell Mol Physiol. 2014 Jun 15;306(12):L1064-77. doi: 10.1152/ajplung.00027.2014. Epub 2014 Apr 11. PMID: 24727584.
https://pubmed.ncbi.nlm.nih.gov/24727584/
De Langhe E, Cailotto F, De Vooght V, Aznar-Lopez C, Vanoirbeek JA, Luyten FP, Lories RJ. Enhanced endogenous bone morphogenetic protein signaling protects against bleomycin induced pulmonary fibrosis. Respir Res. 2015 Mar 15;16(1):38. doi: 10.1186/s12931-015-0202-x. PMID: 25849157; PMCID: PMC4364322.
https://pubmed.ncbi.nlm.nih.gov/25849157/
Dackor RT, Cheng J, Voltz JW, Card JW, Ferguson CD, Garrett RC, Bradbury JA, DeGraff LM, Lih FB, Tomer KB, Flake GP, Travlos GS, Ramsey RW Jr, Edin ML, Morgan DL, Zeldin DC. Prostaglandin E₂ protects murine lungs from bleomycin-induced pulmonary fibrosis and lung dysfunction. Am J Physiol Lung Cell Mol Physiol. 2011 Nov;301(5):L645-55. doi: 10.1152/ajplung.00176.2011. Epub 2011 Aug 19. PMID: 21856819; PMCID: PMC3213994.
https://pubmed.ncbi.nlm.nih.gov/21856819/
Phillips JE, Peng R, Burns L, Harris P, Garrido R, Tyagi G, Fine JS, Stevenson CS. Bleomycin induced lung fibrosis increases work of breathing in the mouse. Pulm Pharmacol Ther. 2012 Aug;25(4):281-5. doi: 10.1016/j.pupt.2011.10.001. Epub 2011 Oct 20. Erratum in: Pulm Pharmacol Ther. 2022 Jun;73-74:102122. PMID: 22024054.
https://pubmed.ncbi.nlm.nih.gov/22024054/
